Liver cancer is the fourth leading cause of cancer-related deaths worldwide, being the second and sixth most common cause of cancer death in men and women, respectively. In patients with cirrhosis, it represents the primary cause of death. Most liver cancers are hepatocellular carcinomas (HCCs), however some patients develop intrahepatic cholangiocarcinomas (ICCs) or rare tumours in non-cirrhotic livers. 

Chronic liver diseases, alcohol consumption, obesity and diabetes, non-alcoholic fatty liver disease (NAFLD), aflatoxins exposure as well as chronic infection with hepatitis B (HBV) or C (HCV), are considered risk factors. Just this month, the 2020 Nobel Prize awarded three scientists for their discovery of HCV, which leads to cirrhosis and liver cancer, and for their valuable contribution to its elimination.

The burden of adult liver cancers and HCC is still increasing and various public health strategies have been developed to prevent and control this trend, which is likely to remain a major global health problem in the decades ahead. ^[1],[2]

EASL is offering the liver community a collection of open-access educational resources on liver cancer, developed with worldwide experts in the field. Please find them below.