Activities to support the surveillance of invasive bacterial vaccines based on diseases in Tbilisi



A) Objective: to introduce an epidemiological surveillance system for bacterial meningitis in children under 5 years of age in Georgia with a special focus on pathogens: Haemophilus influenzae type B (Hib), Streptococcus pneumoniae (Sp) and neiseria meningitidis (Nm). Obtaining the necessary quality data.
• Obtain high-quality data for clinical management, detection and monitoring of antimicrobial susceptibility.
• Development of national capacities for long-term laboratory management of controlled infections.
B) Ways to implement the project:
• The M. Iashvili Central Children's Hospital and the Lugar Laboratory of DCJEC were selected as a sentinel base (both clinical and laboratory);
• Continuous monitoring and supervision of hospital support staff involved in supervision. Ensure proper admission and registration of cases of possible bacterial meningitis admitted to the clinic, in compliance with certain inclusion criteria and protocol. Ensure proper collection, storage, transportation and laboratory examination of cerebrospinal fluid samples from these patients to identify cases caused by the following pathogens: Streptococcus pneumoniae, Haemophilus influenzae type b, Neisseria meningitides.
• The Lugar Laboratory will receive and re-examine crops isolated in the basic core laboratory and store them in the National Culture Repository. As well as PCR examination of frozen samples of cerebrospinal fluid.
• Participate in Basic and Lugar Labs after receiving a Professional Commission (PT) in an External Quality Program (EQA) The World Health Organization (WHO).
• Participate in another EQA component to transport an agreed number of clinical samples and related cultures for re-examination and additional molecular testing at the Regional Reference Laboratory in London.
• Provision of reagents, supplies and costs for the project by the WHO European Office;
• Involvement of children under 5 years of age with suspected bacterial meningitis who are hospitalized at the base of the foundation according to the standard case definition;
• Enter clinical, epidemiological and laboratory data on possible cases of meningitis into a database provided by the World Health Organization and send the results monthly to the World Health Organization/Europe. C) Expected results:
As a result of basic monitoring, it is expected that qualitative data on the etiological factors of bacterial meningitis will be obtained.



Project implementation dates: 01/03/18-30/06/18


Budget: $12,820


The person responsible for the implementation of the project: Rusudan Chlikadze